3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN - Names and Identifiers
Name | 5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
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Synonyms | 2'-F-rUPhosphoramidite 2'-F-dU Phosphoraamidite 5'-O-DMT-2'-F-dU-3'-CEDPA 5'-DMT-2'-F-rU Phosphoramidite 2'-Deoxy-2'-fluoro-5'-O-DMT-Uridine Phosphoramidite 2'-Fluoro-5'-O-DMT-2'-deoxyuridine-3'-CE-Phosphoramidite 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN 5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
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CAS | 146954-75-8
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EINECS | 2017-001-1 |
3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN - Physico-chemical Properties
Molecular Formula | C39H46FN4O8P
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Molar Mass | 748.78 |
Appearance | powder |
Color | white to off-white |
pKa | 9.39±0.10(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN - Risk and Safety
3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN - Introduction
5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: A solid powder substance.
-Solubility: Insoluble in water, but soluble in organic solvents such as dimethyl sulfoxide and acetonitrile.
-Melting point: There is no published melting point data.
-Molecular formula: C44H40FN6O8P.
Use:
5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a biologically active compound, can be used in the field of biochemical research. It may be used as an active unit for the synthesis of DNA and RNA for the Study of the structure and function of nucleic acids.
Method:
No public information is available about the preparation method and detailed chemical synthesis route of this compound.
Safety Information:
Due to the lack of specific toxicological and safety data, for 5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl) the safety data and evaluation of phosphoramidite is limited. In general, when handling such organic compounds, appropriate safety measures should be taken, and proper laboratory practices and personal protective measures should be followed, such as wearing gloves, goggles and masks. It is strongly recommended to operate in a suitable laboratory environment and conduct a toxicity assessment according to the actual situation. In any project where this compound is used, the applicable safe operating procedures and regulations must be followed.
Last Update:2024-04-10 22:29:15